/*!
 * jQuery ClassyGradient
 * www.class.pm
 *
 * Written by Marius Stanciu - Sergiu <marius@class.pm>
 * Licensed under the MIT license www.class.pm/LICENSE-MIT
 * Version 1.1.0
 *
 */

(function($) {
    $.ClassyGradient = function(element, options) {
        var defaults = {
            gradient: '0% #02CDE8, 100% #000000',
            width: 300,
            height: 18,
            point: 8,
            orientation: 'vertical',
            target: null,
            onChange: function() {

            },
            onInit: function() {

            }
        };
        var $element = $(element), _container, _canvas, $pointsContainer, $pointsInfos, $pointsInfosContent, $pointColor, $pointPosition, $btnPointDelete, _context, _selPoint;
        var points = new Array();
        this.settings = {};
        this.__constructor = function() {
            this.settings = $.extend({}, defaults, options);
            this.update();
            this.settings.onInit();
            return this;
        };
        this.update = function() {
            this._setupPoints();
            this._setup();
            this._render();
        };
        this.getCSS = function() {
            var out = '', svgX = '0%', svgY = '100%', webkitDir = 'left bottom', defDir = 'top';
            if (this.settings.orientation === 'horizontal') {
                svgX = '100%';
                svgY = '0%';
                webkitDir = 'right top';
                defDir = 'left';
            }

			defDir = this.settings.orientation; // hack by amit

            var svg = '<svg xmlns="http://www.w3.org/2000/svg">' + '<defs>' + '<linearGradient id="gradient" x1="0%" y1="0%" x2="' + svgX + '" y2="' + svgY + '">';
            var webkitCss = '-webkit-gradient(linear, left top, ' + webkitDir;
            var defCss = '';
            $.each(points, function(i, el) {
                webkitCss += ', color-stop(' + el[0] + ', ' + el[1] + ')';
                defCss += ',' + el[1] + ' ' + el[0] + '';
                svg += '<stop offset="' + el[0] + '" style="stop-color:' + el[1] + ';" />';
            });
            webkitCss += ')';
            defCss = defCss.substr(1);
            svg += '</linearGradient>' + '</defs>' + '<rect fill="url(#gradient)" height="100%" width="100%" />' + '</svg>';
            svg = this._base64(svg);
            out += 'background: url(data:image/svg+xml;base64,' + svg + ');' + '\n';
            out += 'background: ' + webkitCss + ';\n';
            out += 'background: ' + '-moz-linear-gradient(' + defDir + ',' + defCss + ');' + '\n';
            out += 'background: ' + '-webkit-linear-gradient(' + defDir + ',' + defCss + ');' + '\n';
            out += 'background: ' + '-o-linear-gradient(' + defDir + ',' + defCss + ');' + '\n';
            out += 'background: ' + '-ms-linear-gradient(' + defDir + ',' + defCss + ');' + '\n';
            out += 'background: ' + 'linear-gradient(' + defDir + ',' + defCss + ');';
            return out;
        };
        this.getArray = function() {
            return points;
        };
        this.getString = function() {
            var out = '';
            $.each(points, function(i, el) {
                out += el[0] + ' ' + el[1] + ',';
            });
            out = out.substr(0, out.length - 1);
            return out;
        };
        this.setOrientation = function(orientation) {
            this.settings.orientation = orientation;
            this._renderToTarget();
        };
        this._setupPoints = function() {
            points = new Array();
            if ($.isArray(this.settings.gradient)) {
                points = this.settings.gradient;
            }
            else {
                points = this._getGradientFromString(this.settings.gradient);
            }
        };
        this._setup = function() {
            var self = this;
            $element.empty();
            _container = $('<div class="ClassyGradient"></div>');
            _canvas = $('<canvas class="canvas" width="' + this.settings.width + '" height="' + this.settings.height + '"></canvas>');
            _container.append(_canvas);
            _context = _canvas.get(0).getContext('2d');
            $pointsContainer = $('<div class="points"></div>');
            $pointsContainer.css('width', (this.settings.width) + Math.round(this.settings.point / 2 + 1) + 'px');
            _container.append($pointsContainer);
            $pointsInfos = $('<div class="info"></div>');
            $pointsInfos.append('<div class="arrow"></div>');
            _container.append($pointsInfos);
            $pointsInfosContent = $('<div class="content"></div>');
            $pointsInfos.append($pointsInfosContent);
            $element.hover(function() {
                $element.addClass('hover');
            }, function() {
                $element.removeClass('hover');
            });
            $pointColor = $('<div class="point-color"><div style="background-color: #00ff00"></div></div>');
            $pointPosition = $('<span class="point-position">%</span>');
            $btnPointDelete = $('<a href="#" class="delete"></a>');
            $pointsInfosContent.append($pointColor, $pointPosition, $btnPointDelete);
            $element.append(_container);
            $pointColor.ColorPicker({
                color: '#00ff00',
                onSubmit: function(hsb, hex, rgb) {
                    $element.find('.point-color div').css('backgroundColor', '#' + hex);
                    _selPoint.css('backgroundColor', '#' + hex);
                    self._renderCanvas();
                    self._renderToTarget();
                },
                onChange: function(hsb, hex, rgb) {
                    $element.find('.point-color div').css('backgroundColor', '#' + hex);
                    _selPoint.css('backgroundColor', '#' + hex);
                    self._renderCanvas();
                    self._renderToTarget();
                }
            });
            $(document).bind('click', function() {
                if (!$element.is('.hover')) {
                    $pointsInfos.hide('fast');
                }
            });
            _canvas.unbind('click');
            _canvas.bind('click', function(e) {
                var offset = _canvas.offset(), clickPosition = e.pageX - offset.left;
                clickPosition = Math.round((clickPosition * 100) / self.settings.width);
                var defaultColor = '#000000', minDist = 999999999999;
                $.each(points, function(i, el) {
                    if ((parseInt(el[0]) < clickPosition) && (clickPosition - parseInt(el[0]) < minDist)) {
                        minDist = clickPosition - parseInt(el[0]);
                        defaultColor = el[1];
                    }
                    else if ((parseInt(el[0]) > clickPosition) && (parseInt(el[0]) - clickPosition < minDist)) {
                        minDist = parseInt(el[0]) - clickPosition;
                        defaultColor = el[1];
                    }
                });
                points.push([clickPosition + '%', defaultColor]);
                points.sort(self._sortByPosition);
                self._render();
                $.each(points, function(i, el) {
                    if (el[0] == clickPosition + '%') {
                        self._selectPoint($pointsContainer.find('.point:eq(' + i + ')'));
                    }
                });
            });
        };
        this._render = function() {
            this._initGradientPoints();
            this._renderCanvas();
            this._renderToTarget();
        };
        this._initGradientPoints = function() {
            var self = this;
            $pointsContainer.empty();
            $.each(points, function(i, el) {
                $pointsContainer.append('<div class="point" style="background-color: ' + el[1] + '; left:' + (parseInt(el[0]) * self.settings.width) / 100 + 'px;"></div>');
            });
            $pointsContainer.find('.point').css('width', this.settings.point + 'px').css('height', this.settings.point + 'px').mouseup(function() {
                self._selectPoint(this);
            }).draggable({
                axis: 'x',
                containment: 'parent',
                drag: function() {
                    self._selectPoint(this);
                    self._renderCanvas();
                    self._renderToTarget();
                }
            });
        };
        this._selectPoint = function(el) {
            var self = this;
            _selPoint = $(el);
            var color = $(el).css('backgroundColor'), position = parseInt($(el).css('left'));
            position = Math.round((position / this.settings.width) * 100);
            color = color.substr(4, color.length);
            color = color.substr(0, color.length - 1);
            $pointColor.ColorPickerSetColor(this._rgbToHex(color.split(',')));
            $pointColor.find('div').css('backgroundColor', this._rgbToHex(color.split(',')));
            $pointPosition.html('Position: ' + position + '%');
            $btnPointDelete.unbind('click').bind('click', function() {
                if (points.length > 1) {
                    points.splice(_selPoint.index(), 1);
                    self._render();
                    $element.find('.info').hide('fast');
                }
                return false;
            });
            $element.find('.info').css('marginLeft', parseInt($(el).css('left')) - 30 + 'px').show('fast');
        };
        this._renderCanvas = function() {
            var self = this;
            points = new Array();
            $element.find('.point').each(function(i, el) {
                var position = Math.round((parseInt($(el).css('left')) / self.settings.width) * 100);
                var color = $(el).css('backgroundColor').substr(4, $(el).css('backgroundColor').length - 5);
                color = self._rgbToHex(color.split(','));
                points.push([position + '%', color]);
            });
            points.sort(self._sortByPosition);
            this._renderToCanvas();
            this.settings.onChange(this.getString(), this.getCSS(), this.getArray());
        };
        this._renderToElement = function(target, gradient) {
            var svgX = '0%', svgY = '100%', webkitDir = 'left bottom', defDir = 'top';
            if ((target === _canvas) || (this.settings.orientation === 'horizontal')) {
                svgX = '100%';
                svgY = '0%';
                webkitDir = 'right top';
                defDir = 'left';
            }
			
			defDir = this.settings.orientation; // hack by amit
            
			var svg = '<svg xmlns="http://www.w3.org/2000/svg">' + '<defs>' + '<linearGradient id="gradient" x1="0%" y1="0%" x2="' + svgX + '" y2="' + svgY + '">';
            var webkitCss = '-webkit-gradient(linear, left top, ' + webkitDir;
            var defCss = '';
            $.each(gradient, function(i, el) {
                webkitCss += ', color-stop(' + el[0] + ', ' + el[1] + ')';
                defCss += ',' + el[1] + ' ' + el[0] + '';
                svg += '<stop offset="' + el[0] + '" style="stop-color:' + el[1] + ';" />';
            });
            webkitCss += ')';
            defCss = defCss.substr(1);
            svg += '</linearGradient>' + '</defs>';
            if (target === $pointsInfosContent) {
                var tooltipRadius = parseInt($pointsInfosContent.css('borderRadius'));
                svg += '<rect fill="url(#gradient)" height="100%" width="100%" rx="' + tooltipRadius + '" ry="' + tooltipRadius + '" />';
            }
            else {
                svg += '<rect fill="url(#gradient)" height="100%" width="100%" />';
            }
            svg += '</svg>';
            svg = this._base64(svg);
            target.css('background', 'url(data:image/svg+xml;base64,' + svg + ')');
            target.css('background', webkitCss);
            target.css('background', '-moz-linear-gradient(' + defDir + ',' + defCss + ')');
            target.css('background', '-webkit-linear-gradient(' + defDir + ',' + defCss + ')');
            target.css('background', '-o-linear-gradient(' + defDir + ',' + defCss + ')');
            target.css('background', '-ms-linear-gradient(' + defDir + ',' + defCss + ')');
            target.css('background', 'linear-gradient(' + defDir + ',' + defCss + ')');
        };
        this._renderToTarget = function() {
            if (this.settings.target !== null) {
                this._renderToElement($(this.settings.target), points);
            }
        };
        this._renderToCanvas = function() {
            var gradient = _context.createLinearGradient(0, 0, this.settings.width, 0);
            $.each(points, function(i, el) {
                gradient.addColorStop(parseInt(el[0]) / 100, el[1]);
            });
            _context.clearRect(0, 0, this.settings.width, this.settings.height);
            _context.fillStyle = gradient;
            _context.fillRect(0, 0, this.settings.width, this.settings.height);
            this.settings.onChange(this.getString(), this.getCSS(), this.getArray());
        };
        this._getGradientFromString = function(gradient) {
            var arr = new Array(), _t = gradient.split(',');
            $.each(_t, function(i, el) {
                var position;
                if ((el.substr(el.indexOf('%') - 3, el.indexOf('%')) == '100') || (el.substr(el.indexOf('%') - 3, el.indexOf('%')) == '100%')) {
                    position = '100%';
                }
                else if (el.indexOf('%') > 1) {
                    position = parseInt(el.substr(el.indexOf('%') - 2, el.indexOf('%')));
                    position += '%';
                }
                else {
                    position = parseInt(el.substr(el.indexOf('%') - 1, el.indexOf('%')));
                    position += '%';
                }
                var color = el.substr(el.indexOf('#'), 7);
                arr.push([position, color]);
            });
            return arr;
        };
        this._rgbToHex = function(rgb) {
            var R = rgb[0], G = rgb[1], B = rgb[2];
            function toHex(n) {
                n = parseInt(n, 10);
                if (isNaN(n))
                    return "00";
                n = Math.max(0, Math.min(n, 255));
                return "0123456789ABCDEF".charAt((n - n % 16) / 16) + "0123456789ABCDEF".charAt(n % 16);
            }
            return '#' + toHex(R) + toHex(G) + toHex(B);
        };
        this._sortByPosition = function(data_A, data_B) {
            if (parseInt(data_A[0]) < parseInt(data_B[0])) {
                return -1;
            }
            if (parseInt(data_A[0]) > parseInt(data_B[0])) {
                return 1;
            }
            return 0;
        };
        this._base64 = function(input) {
            var keyStr = "ABCDEFGHIJKLMNOPQRSTUVWXYZabcdefghijklmnopqrstuvwxyz0123456789+/=", output = "", chr1, chr2, chr3, enc1, enc2, enc3, enc4, i = 0;
            while (i < input.length) {
                chr1 = input.charCodeAt(i++);
                chr2 = input.charCodeAt(i++);
                chr3 = input.charCodeAt(i++);
                enc1 = chr1 >> 2;
                enc2 = ((chr1 & 3) << 4) | (chr2 >> 4);
                enc3 = ((chr2 & 15) << 2) | (chr3 >> 6);
                enc4 = chr3 & 63;
                if (isNaN(chr2)) {
                    enc3 = enc4 = 64;
                }
                else if (isNaN(chr3)) {
                    enc4 = 64;
                }
                output += keyStr.charAt(enc1) + keyStr.charAt(enc2) + keyStr.charAt(enc3) + keyStr.charAt(enc4);
            }
            return output;
        };
        return this.__constructor();
    };
    $.fn.ClassyGradient = function(options) {
        return this.each(function() {
            if ($(this).data('ClassyGradient') === undefined) {
                var plugin = new $.ClassyGradient(this, options);
                $(this).data('ClassyGradient', plugin);
            }
        });
    };
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		<meta property="og:description" content="Die positiven Wirkungen von Letrozol Letrozol ist ein Medikament, das häufig zur Behandlung von hormonempfindlichem Brustkrebs eingesetzt wird. Es gehört zur Klasse der Aromatasehemmer und wirkt durch die Hemmung der letrozol legal Östrogenproduktion im Körper. Diese letrozol Positive Wirkungen sind entscheidend für viele Patientinnen, die sich einer Therapie gegen Brustkrebs unterziehen. Wie funktioniert Letrozol? Letrozol" />
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	<h2 class="single-post-title entry-title" itemprop="headline">Die positiven Wirkungen von Letrozol</h2><!-- .single-post-title -->
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	<h1>Die positiven Wirkungen von Letrozol</h1>
<p>Letrozol ist ein Medikament, das häufig zur Behandlung von hormonempfindlichem Brustkrebs eingesetzt wird. Es gehört zur Klasse der Aromatasehemmer und wirkt durch die Hemmung der <a href="https://letrozolonline.com/">letrozol legal</a> Östrogenproduktion im Körper. Diese <strong>letrozol Positive Wirkungen</strong> sind entscheidend für viele Patientinnen, die sich einer Therapie gegen Brustkrebs unterziehen.</p>
<h2>Wie funktioniert Letrozol?</h2>
<p>Letrozol blockiert das Enzym Aromatase, das für die Umwandlung von Androgenen in Östrogene verantwortlich ist. Durch diese Hemmung wird der Östrogenspiegel im Körper gesenkt, was besonders wichtig ist, da viele Brusttumoren auf Östrogen reagieren. Die letrozol Positive Wirkungen zeigen sich vor allem in der Verlangsamung des Tumorwachstums und in der Reduzierung des Rückfallrisikos.</p>
<h3>Vorteile von Letrozol</h3>
<p>Die Anwendung von Letrozol hat mehrere Vorteile:</p>
<ul>
<li><strong>Effektive Tumorbehandlung:</strong> Studien haben gezeigt, dass Letrozol bei vielen Frauen mit hormonempfindlichem Brustkrebs effektiver ist als andere Behandlungsformen.</li>
<li><strong>Reduziertes Risiko für Rückfälle:</strong> Der Einsatz von Letrozol nach der Operation kann das Risiko eines Rückfalls signifikant senken.</li>
<li><strong>Bessere Verträglichkeit:</strong> Viele Patientinnen berichten von einer besseren Verträglichkeit im Vergleich zu anderen Hormontherapien.</li>
</ul>
<h2>Zusätzliche positive Effekte</h2>
<p>Abgesehen von den direkten Auswirkungen auf den Brustkrebs gibt es auch letrozol Positive Wirkungen, die über die Behandlung hinausgehen:</p>
<ul>
<li><strong>Verbesserte Lebensqualität:</strong> Einige Patientinnen berichten von einer Verbesserung ihrer allgemeinen Lebensqualität während der Einnahme von Letrozol.</li>
<li><strong>Wissenschaftliche Unterstützung:</strong> Zahlreiche Studien unterstützen die Verwendung von Letrozol als Standardtherapie, was das Vertrauen in die Behandlung stärkt.</li>
</ul>
<h3>Fazit</h3>
<p>Zusammenfassend lässt sich sagen, dass <strong>letrozol Positive Wirkungen</strong> sowohl auf physischer als auch auf emotionaler Ebene erkennbar sind. Die gezielte Senkung des Östrogenspiegels hilft nicht nur bei der Bekämpfung des Brustkrebses, sondern verbessert auch die Lebensqualität vieler Patientinnen. Es ist wichtig, dass betroffene Frauen in enger Absprache mit ihrem Arzt die besten Behandlungsoptionen auswählen.</p>

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